1)JAWS - most compatible with Chrome , firefox and Internet explorer although it supports other browsers as well. It is expensive. Compatible only with windows OS. JAWS came in the market much before NVDA and is a slightly better as compared to NVDA for blind uers because of better braille support , more sounds and whistles and more configuration options. But still it's a better deal to use a free NVDA than to pay a heavy price for JAWS. Hence the users have now been shifting to NVDA and popularity of JAWS is decreasing. 2) NVDA- most compatible with Chrome , firefox and Edge although it supports other browsers as well. It is free of cost. Compatible only with windows OS 3)Voiceover- Available and used by default with Macos(Mac laptops) and IOS(Iphones) 4)Talkback - Available and used by default with Android phones